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Recent advances in the molecular mechanism of sex disparity in hepatocellular carcinoma (Review)

8 Mar 2019

Abstract excerpt

Hepatocellular carcinoma (HCC) is more frequently observed and aggressive in men compared with women. Increasing evidence demonstrates that the sex disparity appears to be mediated by the stimulatory effects of androgens and the protective effects of estrogen in the development and progression of HCC. In the past few decades, studies on the sex difference of HCC mainly focused on the effect of sex hormones on the...

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Share to Genomics, phytochemicals, and oxidative stress
Share to Hepatocellular Carcinoma Treatment and Prognosis
Share to Liver Disease Diagnosis and Treatment

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PMID: 30988804
DOI: 10.3892/ol.2019.10127

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