Article
Genetic robustness and functional evolution of gene duplicates.
Nucleic acids research - 1 Feb 2014
Plata Germán, Vitkup Dennis
Abstract excerpt
Gene duplications are a major source of evolutionary innovations. Understanding the functional divergence of duplicates and their role in genetic robustness is an important challenge in biology. Previously, analyses of genetic robustness were primarily focused on duplicates essentiality and epistasis in several laboratory conditions. In this study, we use several quantitative data sets to understand compensatory...
Topics
- Evolution, Molecular
- Gene Duplication
- Genes, Fungal
- Phenotype
- Saccharomyces cerevisiae