Article
skn-1 is required for interneuron sensory integration and foraging behavior in Caenorhabditis elegans.
PloS one - 1 Jan 2017
Wilson Mark A, Iser Wendy B, Son Tae Gen, Logie Anne, Cabral-Costa Joao V, Mattson Mark P, Camandola Simonetta
Abstract excerpt
Nrf2/skn-1, a transcription factor known to mediate adaptive responses of cells to stress, also regulates energy metabolism in response to changes in nutrient availability. The ability to locate food sources depends upon chemosensation. Here we show that Nrf2/skn-1 is expressed in olfactory interneurons, and is required for proper integration of multiple food-related sensory cues in Caenorhabditis elegans....
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