Article
A mass graph-based approach for the identification of modified proteoforms using top-down tandem mass spectra.
Bioinformatics (Oxford, England) - 1 May 2017
Kou Qiang, Wu Si, Tolic Nikola, Paša-Tolic Ljiljana, Liu Yunlong, Liu Xiaowen
Abstract excerpt
Motivation: Although proteomics has rapidly developed in the past decade, researchers are still in the early stage of exploring the world of complex proteoforms, which are protein products with various primary structure alterations resulting from gene mutations, alternative splicing, post-translational modifications, and other biological processes. Proteoform identification is essential to mapping proteoforms to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.