Article

Spritz: A Proteogenomic Database Engine

2020-06-09

Abstract excerpt

Proteoforms are the workhorses of the cell, and subtle differences between their amino acid sequence or post-translational modifications (PTMs) can change their biological function. To most effectively identify and quantify proteoforms in genetically diverse samples by mass spectrometry (MS), it is advantageous to search the MS data against a sample-specific protein database that is tailored to the sample being an...

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Literature Corpus work: a2eb04c2-0010-5553-8add-b95188344fe6
DOI: 10.1101/2020.06.08.140681

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