Article
Use of GeneXpert Remnants for Drug Resistance Profiling and Molecular Epidemiology of Tuberculosis in Libreville, Gabon.
Journal of clinical microbiology - 1 Jul 2017
Alame-Emane Amel Kévin, Pierre-Audigier Catherine, Aboumegone-Biyogo Oriane Cordelia, Nzoghe-Mveang Amandine, Cadet-Daniel Véronique, Sola Christophe, Djoba-Siawaya Joël Fleury, Gicquel Brigitte, Takiff Howard E
Abstract excerpt
Multidrug-resistant (MDR) and extensively drug resistant (XDR) strains of Mycobacterium tuberculosis pose major problems for global health. The GeneXpert MTB/RIF (Xpert) assay rapidly detects resistance to rifampin (RIFr), but for detection of the additional resistance that defines MDR-TB (MDR tuberculosis) and XDR-TB, and for molecular epidemiology, specimen cultures and a biosafe infrastructure are generally...
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