Article
Obesity and associated lifestyles modify the effect of glucose metabolism-related genetic variants on impaired glucose homeostasis among postmenopausal women.
Genetic epidemiology - 1 Sept 2016
Jung Su Yon, Sobel Eric M, Papp Jeanette C, Crandall Carolyn J, Fu Alan N, Zhang Zuo-Feng
Abstract excerpt
PURPOSE: Impaired glucose metabolism-related genetic variants likely interact with obesity-modifiable factors in response to glucose intolerance, yet their interconnected pathways have not been fully characterized. METHODS: With data from 1,027 postmenopausal participants of the Genomics and Randomized Trials Network study and 15 single-nucleotide polymorphisms (SNPs) associated with glucose homeostasis, we...
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