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Article

Loss of heterozygosity in FANCG, FANCF and BRIP1 from head and neck squamous cell carcinoma of the oral cavity.

International journal of oncology - 1 Jun 2017

Türke Christin, Horn Susanne, Petto Carola, Labudde Dirk, Lauer Günter, Wittenburg Gretel

Abstract excerpt

Recent advances have been made in the understanding of Fanconi anemia (FA), a hereditary disease that increases the risk for head and neck squamous cell carcinomas (HNSCC) by 500- to 700-fold. FA patients harbour germline mutations in genes of cellular DNA repair pathways that are assumed to facilitate the accumulation of mutations during HNSCC development. Mutations in these FA genes may also contribute to HNSCC...

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Source

Identifiers

PMID: 28440438
DOI: 10.3892/ijo.2017.3974

Genes

FANCF
BRIP1
FANCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Loss of heterozygosity in FANCG, FANCF and BRIP1 from head and neck squamous cell carcinoma of the oral cavity.PMID 28440438Read ↗

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