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Two enemies, one fight: An update of oral cancer in patients with Fanconi anemia

7 Aug 2019

Abstract excerpt

Fanconi anemia (FA) is a rare inherited genetic condition that may lead to bone marrow failure, leukemia, and/or solid tumors. It is caused by the loss of function of at least 1 gene of the FA/BRCA pathway, which is necessary for DNA repair. Patients with FA have a 200-fold to 1000-fold risk of developing head and neck cancer, mainly oral squamous cell carcinoma (OSCC), and of doing so at a much younger age than...

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PMID: 31390058
DOI: 10.1002/cncr.32435

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