Article
A SNP involved in alternative splicing of ABCB1 is associated with clopidogrel resistance in coronary heart disease in Chinese population.
Aging - 20 Nov 2020
Zhang Shasha, Wang Jing, Zhang Anan, Zhang Xiaowei, You Tao, Xie Dingxiong, Yang Wenke, Chen Yuhong, Zhang Xuetian, Di Cuixia, Xie Xiaodong
Abstract excerpt
Although many scientists are studying the association between genetic polymorphism of ABCB1 and CR in patients, the molecular mechanism has not been further studied in patients with CHD. This study investigated the relationship between SNP of the ABCB1 gene in patients with CHD and CR, and whether the polymorphism of the ABCB1 gene affects the AS of the gene. 741 patients were enrolled in the study, 316 CR cases...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.