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Article

Genotypic adaptations associated with prolonged persistence of Lactobacillus plantarum in the murine digestive tract.

Biotechnology journal - 1 Aug 2013

van Bokhorst-van de Veen Hermien, Smelt Maaike J, Wels Michiel, van Hijum Sacha A F T, de Vos Paul, Kleerebezem Michiel, Bron Peter A

Abstract excerpt

Probiotic bacteria harbor effector molecules that confer health benefits, but also adaptation factors that enable them to persist in the gastrointestinal tract of the consumer. To study these adaptation factors, an antibiotic-resistant derivative of the probiotic model organism Lactobacillus plantarum WCFS1 was repeatedly exposed to the mouse digestive tract by three consecutive rounds of (re)feeding of the...

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PMID: 24066356
DOI: 10.1002/biot.201200259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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