Article
Issues in current microRNA target identification methods.
RNA biology - 3 Jul 2017
Seitz Hervé
Abstract excerpt
microRNAs are currently believed to control a large diversity of physiologic processes, through the collective repression of thousands of target genes. Both experimental and computational analyses indeed suggest that each microRNA regulates tens or hundreds of genes. But some observations suggest that the phenotypic consequences of many published miRNA/mRNA interactions are dubious. For example, the reported...
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