Article
The micro RNA target paradigm: a fundamental and polymorphic control layer of cellular expression.
Expert opinion on biological therapy - 1 Sept 2007
Barnes Michael R, Deharo Steve, Grocock Russell J, Brown James R, Sanseau Philippe
Abstract excerpt
Evidence is emerging that micro RNA (miRNA) is an important and potentially polymorphic regulatory layer for silencing gene expression in vivo. Knowledge of miRNA targeting may help to elucidate the function of many human genes in common diseases, providing a powerful target validation technology. Accurate in silico prediction of miRNA targets in mRNA is a critical capability, allowing effective evaluation of the...
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