Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of Dominant Negative K6W-Ubiquitin in the Lens Epithelium via an Adenoviral Vector Delays Posterior Capsule Opacification in a Rabbit Model.

Current molecular medicine - 1 Jan 2017

Bao X, Hou M, Peng R, Luo F, Wu M

Abstract excerpt

PURPOSE: Ubiquitin is involved in cell proliferation and differentiation, and the objective of this study is to investigate the potential of dominant negative Ubiquitin (Ub) with a lysine to tryptophan mutation at the 6 position (K6W) through an adenoviral expression vector in the prevention of posterior capsule opacification (PCO) in a rabbit PCO model. METHODS: Recombinant dominant negative K6W-Ub adenovirus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Adenoviridae
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lens, Crystalline

Share to Proteasome Endopeptidase Complex

Share to Rabbits

Share to Transduction, Genetic

Share to Ubiquitin

Source

Identifiers

PMID: 28429670
DOI: 10.2174/1566524017666170331163751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Expression of Dominant Negative K6W-Ubiquitin in the Lens Epithelium via an Adenoviral Vector Delays Posterior Capsule Opacification in a Rabbit Model.PMID 28429670Read ↗

Poxvirus Exploitation of the Ubiquitin-Proteasome SystemSemantic proximity Read ↗

CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts.Semantic proximity Read ↗

The deubiquitylase USP10 regulates integrin β1 and β5 and fibrotic wound healingSemantic proximity Read ↗

AAV2/9-mediated gene transfer into murine lacrimal gland leads to a long-term targeted tear film modificationSemantic proximity Read ↗

Role of Decorin in the Lens and Ocular DiseasesSemantic proximity Read ↗

Corneal fibrosis abrogation by a localized AAV-mediated inhibitor of differentiation 3 (Id3) gene therapy in rabbit eyes in vivoSemantic proximity Read ↗

High Levels of Serum Ubiquitin and Proteasome in a Case of HLA-B27 Uveitis.Semantic proximity Read ↗

PAX6, modified by SUMOylation, plays a protective role in corneal endothelial injurySemantic proximity Read ↗

Ubiquitin fusion technique and its descendants.Semantic proximity Read ↗

Changes in Corneal Innervation after HSV-1 Latency Established with Different Reactivation Phenotypes.Semantic proximity Read ↗

Effects of the loss of conjunctival Muc16 on corneal epithelium and stroma in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.