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Article

Association of NF-κB polymorphisms with clinical outcome of non-medullary thyroid carcinoma.

Endocrine-related cancer - 1 Jul 2017

Plantinga Theo S, Petrulea Mirela S, Oosting Marije, Joosten Leo A B, Piciu Doina, Smit Johannes W, Netea-Maier Romana T, Georgescu Carmen E

Abstract excerpt

The NF-κB inflammatory pathway plays a major role in cancer development and clinical progression. Activation of NF-κB signaling is promoted by NFKB1 and inhibited by NFKBIA. The present study aimed to determine the relevance of NFKB1 rs4648068 and NFKBIA rs2233406 genetic variants for non-medullary thyroid cancer (NMTC) susceptibility, progression and clinical outcome. This case-control and cohort study consists...

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Source

Identifiers

PMID: 28428267
DOI: 10.1530/ERC-17-0033

Genes

NFKBIA
NFKB1
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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