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Article

Causal effect of thyroid cancer on secondary primary malignancies: findings from the UK Biobank and FinnGen cohorts.

Frontiers in immunology - 1 Jan 2024

Wang Zhengshi, Rixiati Youlutuziayi, Jia Chengyou, Xu Yong, Yin Zhiqiang, Huang Junwen, Dai Jiaqi, Zhang Yun

Abstract excerpt

Background: Existing epidemiological data indicated a correlation between thyroid cancer (THCA) and the risk of secondary primary malignancies (SPMs). However, the correlation does not always imply causality. Methods: The Mendelian randomization (MR) analyses were performed to investigate the causal relationships between THCA and SPMs based on international multicenter data. Odds ratios (ORs) with 95% confidence...

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Identifiers

PMID: 39391305
DOI: 10.3389/fimmu.2024.1434737
PMCID: PMC11464368

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