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Article

A functional insertion/deletion polymorphism in the promoter region of the NFKB1 gene increases the risk of papillary thyroid carcinoma.

Genetic testing and molecular biomarkers - 1 Mar 2015

Wang Xunli, Peng Hong, Liang Yundan, Sun Ruifen, Wei Tao, Li Zhihui, Gong Yanping, Gong Rixiang, Liu Feng, Zhang Lin, Zhu Jingqiang

Abstract excerpt

This study aimed to assess whether an insertion/deletion polymorphic variation rs28362491 in the NFKB1 promoter region was related to the risk of papillary thyroid carcinoma (PTC). Genomic DNA was extracted from the peripheral venous blood of 352 patients with PTC and 459 controls. The NFKB1 rs28362491 polymorphism was genotyped by using a polymerase chain reaction assay. We found that the frequency of the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 25692306
DOI: 10.1089/gtmb.2014.0271
PMCID: PMC4361360

Genes

NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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