Article
Apolipoprotein M gene (APOM) polymorphism modifies metabolic and disease traits in type 2 diabetes.
PloS one - 24 Feb 2011
Zhou Jun-Wei, Tsui Stephen K W, Ng Maggie C Y, Geng Hua, Li Sai-Kam, So Wing-Yee, Ma Ronald C, Wang Ying, Tao Qian, Chen Zhen-Yu, Chan Juliana C N, Ho Yuan-Yuan
Abstract excerpt
This study aimed at substantiating the associations of the apolipoproein M gene (APOM) with type 2 diabetes (T2D) as well as with metabolic traits in Hong Kong Chinese. In addition, APOM gene function was further characterized to elucidate its activity in cholesterol metabolism. Seventeen APOM SNPs documented in the NCBI database were genotyped. Five SNPs were confirmed in our study cohort of 1234 T2D and 606...
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