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Article

Association between familial hypercholesterolemia and prevalence of type 2 diabetes mellitus.

JAMA - 10 Mar 2015

Besseling Joost, Kastelein John J P, Defesche Joep C, Hutten Barbara A, Hovingh G Kees

Abstract excerpt

IMPORTANCE: Familial hypercholesterolemia is characterized by impaired uptake of cholesterol in peripheral tissues, including the liver and the pancreas. In contrast, statins increase the cellular cholesterol uptake and are associated with increased risk for type 2 diabetes mellitus. We hypothesi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25756439
DOI: 10.1001/jama.2015.1206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25756439-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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