Association of APOE polymorphisms with diabetes and cardiometabolic risk factors and the role of APOE genotypes in response to anti-diabetic therapy: results from the AIDHS/SDS on a South Asian population.

doi:10.1016/j.jdiacomp.2015.07.025

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Article

Association of APOE polymorphisms with diabetes and cardiometabolic risk factors and the role of APOE genotypes in response to anti-diabetic therapy: results from the AIDHS/SDS on a South Asian population.

Journal of diabetes and its complications - 1 Jan 2000

Sapkota Bishwa, Subramanian Anuradha, Priamvada Gargi, Finely Hadley, Blackett Piers R, Aston Christopher E, Sanghera Dharambir K

Abstract excerpt

BACKGROUND AND OBJECTIVES: Apolipoprotein E (APOE) gene polymorphisms have been examined extensively in multiple global populations particularly due to their crucial role in lipid metabolism and cardiovascular disease. However, the overall contribution of APOE polymorphisms in type 2 diabetes (T2D) and coronary artery disease (CAD) in South Asians is still under-investigated. The objectives of this investigation...

Topics

Alleles
Apolipoprotein E3
Case-Control Studies
Cohort Studies
Coronary Artery Disease
Diabetes Mellitus, Type 2
Diabetic Angiopathies
Drug Resistance
Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Gene Frequency

Genetic Association Studies

Genetic Predisposition to Disease

Humans

Hyperglycemia

Hyperlipidemias

Hypoglycemic Agents

India

Source

Open in PubMed Open full text

Identifiers

PMID: 26318958
DOI: 10.1016/j.jdiacomp.2015.07.025
PMCID: PMC4656127

Genes

APOE
CAD
SDS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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