Article
Next generation mapping reveals novel large genomic rearrangements in prostate cancer.
Oncotarget - 4 Apr 2017
Jaratlerdsiri Weerachai, Chan Eva K F, Petersen Desiree C, Yang Claire, Croucher Peter I, Bornman M S Riana, Sheth Palak, Hayes Vanessa M
Abstract excerpt
Complex genomic rearrangements are common molecular events driving prostate carcinogenesis. Clinical significance, however, has yet to be fully elucidated. Detecting the full range and subtypes of large structural variants (SVs), greater than one kilobase in length, is challenging using clinically feasible next generation sequencing (NGS) technologies. Next generation mapping (NGM) is a new technology that allows...
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