Article
Mate pair sequencing of whole-genome-amplified DNA following laser capture microdissection of prostate cancer.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Oct 2012
Murphy Stephen J, Cheville John C, Zarei Shabnam, Johnson Sarah H, Sikkink Robert A, Kosari Farhad, Feldman Andrew L, Eckloff Bruce W, Karnes R Jeffrey, Vasmatzis George
Abstract excerpt
High-throughput next-generation sequencing provides a revolutionary platform to unravel the precise DNA aberrations concealed within subgroups of tumour cells. However, in many instances, the limited number of cells makes the application of this technology in tumour heterogeneity studies a challenge. In order to address these limitations, we present a novel methodology to partner laser capture microdissection...
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