C3orf21 ablation promotes the proliferation of lung adenocarcinoma, and its mutation at the rs2131877 locus may serve as a susceptibility marker.

doi:10.18632/oncotarget.16798

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Article

C3orf21 ablation promotes the proliferation of lung adenocarcinoma, and its mutation at the rs2131877 locus may serve as a susceptibility marker.

Oncotarget - 16 May 2017

Yang Litao, Wang Ying, Fang Meiyu, Deng Douhou, Zhang Yongjun

Abstract excerpt

In this study, we investigated the role of C3orf21 gene polymorphism at the rs2131877 locus and its contribution to lung adenocarcinoma pathogenesis. Normal lung and tumor tissue sections were collected from fifteen patients with lung adenocarcinoma for chromosome 3 open reading frame 21 (C3orf21) genotype analysis. In addition, a retrospective analysis was performed to assess the association between C3orf21...

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PMID: 28422717
DOI: 10.18632/oncotarget.16798
PMCID: PMC5464879

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