Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.

Cell reports - 10 Jan 2017

Cho Gun-Sik, Lee Dong I, Tampakakis Emmanouil, Murphy Sean, Andersen Peter, Uosaki Hideki, Chelko Stephen, Chakir Khalid, Hong Ingie, Seo Kinya, Chen Huei-Sheng Vincent, Chen Xiongwen, Basso Cristina, Houser Steven R, Tomaselli Gordon F, O'Rourke Brian, Judge Daniel P, Kass David A, Kwon Chulan

Abstract excerpt

Pluripotent stem cells (PSCs) offer unprecedented opportunities for disease modeling and personalized medicine. However, PSC-derived cells exhibit fetal-like characteristics and remain immature in a dish. This has emerged as a major obstacle for their application for late-onset diseases. We previously showed that there is a neonatal arrest of long-term cultured PSC-derived cardiomyocytes (PSC-CMs). Here, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathies
Share to Cell Shape

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mouse Embryonic Stem Cells

Share to Myocardial Contraction

Share to Myocytes, Cardiac

Share to Pluripotent Stem Cells

Share to Single-Cell Analysis

Share to Stem Cell Transplantation

Source

Open in PubMed Open full text

Identifiers

PMID: 28076798
DOI: 10.1016/j.celrep.2016.12.040
PMCID: PMC5232412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.PMID 28076798Read ↗

Maturation strategies and limitations of induced pluripotent stem cell-derived cardiomyocytes.Semantic proximity Read ↗

Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells: Current Strategies and Limitations.Semantic proximity Read ↗

Structural and Functional Maturation of Cardiomyocytes Derived from Human Pluripotent Stem CellsSemantic proximity Read ↗

Mitochondrial Maturation in Human Pluripotent Stem Cell Derived CardiomyocytesSemantic proximity Read ↗

Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes: a Critical Step for Drug Development and Cell Therapy.Semantic proximity Read ↗

Cardiomyocyte Proliferation and Maturation: Two Sides of the Same Coin for Heart RegenerationSemantic proximity Read ↗

<i>In vivo</i> bioreactor matures iPSC-CMs for MLP disease modelingSemantic proximity Read ↗

Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat HeartsSemantic proximity Read ↗

The long and winding road of cardiomyocyte maturation.Semantic proximity Read ↗

Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

Ultrastructural Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Long-Term CultureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.