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Article

Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008-2012.

Emerging infectious diseases - 1 May 2017

Yeh Chau-Ting, Liang Kung-Hao, Chang Ming-Ling, Hsu Chao-Wei, Chen Yi-Cheng, Lin Chih-Lang, Lin Wey-Ran, Lai Ming-Wei

Abstract excerpt

We examined the characteristic changes of hepatitis B virus (HBV) in antiviral drug treatment-naive patients referred for pretreatment evaluation in Taiwan during 2008-2012. Over time, we observed substantial decreases in the prevalence of HBV e antigen (HBeAg) and increasing prevalence of the precore G1899A mutation and HBV-DNA levels in HBeAg-positive patients.

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Identifiers

PMID: 28418295
DOI: 10.3201/eid2305.161894
PMCID: PMC5403058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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