Article
Change of hepatitis B virus genotypes in acute and chronic infections in Japan.
Journal of medical virology - 1 Nov 2008
Kobayashi Mariko, Ikeda Kenji, Arase Yasuji, Suzuki Fumitaka, Akuta Norio, Hosaka Tetsuya, Sezaki Hitomi, Yatsuji Hiromi, Kobayashi Masahiro, Suzuki Yoshiyuki, Watahiki Sachiyo, Mineta Rie, Iwasaki Satomi, Miyakawa Yuzo, Kumada Hiromitsu
Abstract excerpt
During 35 years from 1971 to 2005, 153 patients with acute and 4,277 with chronic HBV infection visited the Toranomon Hospital in Tokyo, Japan. They were grouped into seven 5-year periods, and HBV genotypes/subgenotypes were determined. Patients with acute HBV infection were younger (P = 0.046), predominantly male (P = 0.004), possessed higher alanine aminotransferase levels (P < 0.001), positive more frequently...
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