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Article

The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients.

Oncotarget - 25 Jul 2017

Peng Junjie, Huang Dan, Poston Graeme, Ma Xiaoji, Wang Renjie, Sheng Weiqi, Zhou Xiaoyan, Zhu Xiaoli, Cai Sanjun

Abstract excerpt

PURPOSE: To assess the biological variability of clinical meaningful molecular markers and their clinical correlations in Chinese patients with colorectal cancer (CRC). MATERIALS AND METHODS: In this prospective observational study, frequencies and clinico-pathological features of RAS and BRAFV600E mutations, deficiency of DNA mismatch repair (dMMR) were evaluated in patients with colorectal cancer staged I-IV....

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Identifiers

PMID: 28416767
DOI: 10.18632/oncotarget.16176
PMCID: PMC5564750

Genes

BRAF
KRAS
NRAS

Variants

Provenance

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