Article
The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients.
Oncotarget - 25 Jul 2017
Peng Junjie, Huang Dan, Poston Graeme, Ma Xiaoji, Wang Renjie, Sheng Weiqi, Zhou Xiaoyan, Zhu Xiaoli, Cai Sanjun
Abstract excerpt
PURPOSE: To assess the biological variability of clinical meaningful molecular markers and their clinical correlations in Chinese patients with colorectal cancer (CRC). MATERIALS AND METHODS: In this prospective observational study, frequencies and clinico-pathological features of RAS and BRAFV60...
Topics
- Aged
- Aged, 80 and over
- Asian People
- Biomarkers, Tumor
- China
- Colorectal Neoplasms
- DNA Mismatch Repair
- Exons
- Female
- Genetic Heterogeneity
- Humans
- Male
- Middle Aged
- Mutation
- Neoplasm Grading
- Neoplasm Staging
- Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins p21(ras)