Article
iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types.
Stem cell reports - 11 Apr 2017
Panopoulos Athanasia D, D'Antonio Matteo, Benaglio Paola, Williams Roy, Hashem Sherin I, Schuldt Bernhard M, DeBoever Christopher, Arias Angelo D, Garcia Melvin, Nelson Bradley C, Harismendy Olivier, Jakubosky David A, Donovan Margaret K R, Greenwald William W, Farnam KathyJean, Cook Megan, Borja Victor, Miller Carl A, Grinstein Jonathan D, Drees Frauke, Okubo Jonathan, Diffenderfer Kenneth E, Hishida Yuriko, Modesto Veronica, Dargitz Carl T, Feiring Rachel, Zhao Chang, Aguirre Aitor, McGarry Thomas J, Matsui Hiroko, Li He, Reyna Joaquin, Rao Fangwen, O'Connor Daniel T, Yeo Gene W, Evans Sylvia M, Chi Neil C, Jepsen Kristen, Nariai Naoki, Müller Franz-Josef, Goldstein Lawrence S B, Izpisua Belmonte Juan Carlos, Adler Eric, Loring Jeanne F, Berggren W Travis, D'Antonio-Chronowska Agnieszka, Smith Erin N, Frazer Kelly A
Abstract excerpt
Large-scale collections of induced pluripotent stem cells (iPSCs) could serve as powerful model systems for examining how genetic variation affects biology and disease. Here we describe the iPSCORE resource: a collection of systematically derived and characterized iPSC lines from 222 ethnically diverse individuals that allows for both familial and association-based genetic studies. iPSCORE lines are pluripotent...
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