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Article

IDH1 R132C mutation is detected in clear cell hepatocellular carcinoma by pyrosequencing.

World journal of surgical oncology - 12 Apr 2017

Lee Jung Hee, Shin Dong Hoon, Park Won Young, Shin Nari, Kim Ahrong, Lee Hyun Jung, Kim Young Keum, Choi Kyung Un, Kim Jee Yeon, Yang Young Il, Lee Chang Hun, Sol Mee Young

Abstract excerpt

BACKGROUND: Isocitrate dehydrogenase 1 (IDH1) mutation is common in low-grade glioma (approximately 80%) and acute myeloid leukemia (approximately 10%). Other than brain tumor or hematologic malignancies, intrahepatic cholangiocarcinoma (iCC) is a well-known solid tumor with IDH1 mutation (6.8-20%). Histologically, poor differentiation and clear cell change are associated with IDH1 mutation in iCC. Since...

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Share to Adenocarcinoma, Clear Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28403884
DOI: 10.1186/s12957-017-1144-1
PMCID: PMC5389153

Genes

IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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