Article
Distinct clinical and prognostic implication of IDH1/2 mutation and other most frequent mutations in large duct and small duct subtypes of intrahepatic cholangiocarcinoma.
BMC cancer - 15 Apr 2020
Ma Bingqi, Meng Huijuan, Tian Ye, Wang Yingying, Song Tianqiang, Zhang Ti, Wu Qiang, Cui Yunlong, Li Huikai, Zhang Wei, Li Qiang
Abstract excerpt
BACKGROUND: Isocitrate dehydrogenase 1/2 (IDH1/2), BAP1, ARID1A and PBRM1 have been reported as the most frequent mutant genes in intrahepatic cholangiocarcinoma (ICC), and their relationships with clinicopathological features and prognosis were researched in this study. METHODS: We collected clinical data of 130 ICC patients from January 2012 to December 2017. The IDH1/2 mutation and loss of BAP1, ARID1A and...
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