Article

Signaling through the Dystrophin Glycoprotein Complex affects the stress-dependent transcriptome in Drosophila

2022-06-17

Abstract excerpt

The Dystrophin Glycoprotein Complex (DGC) is a cell membrane-spanning complex that links the extracellular matrix with the intracellular cytoskeleton. Deficiencies in the DGC in humans cause muscular dystrophies (MDs), a group of inherited, incurable disorders associated with heterogeneous muscle, brain, and eye anomalies. To advance disease diagnostics and develop new treatment strategies, it is essential to unde...

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Literature Corpus work: 05ea7fe8-c223-5a21-80cc-9bc4a9236fa4
DOI: 10.1101/2022.06.15.496303

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