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Article

Perlecan regulates bidirectional Wnt signaling at the Drosophila neuromuscular junction.

The Journal of cell biology - 21 Jan 2013

Kamimura Keisuke, Ueno Kohei, Nakagawa Jun, Hamada Rie, Saitoe Minoru, Maeda Nobuaki

Abstract excerpt

Heparan sulfate proteoglycans (HSPGs) play pivotal roles in the regulation of Wnt signaling activity in several tissues. At the Drosophila melanogaster neuromuscular junction (NMJ), Wnt/Wingless (Wg) regulates the formation of both pre- and postsynaptic structures; however, the mechanism balancin...

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Identifiers

PMID: 23319599
DOI: 10.1083/jcb.201207036
PMCID: PMC3549968

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23319599-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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