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Association of the rs8720 and rs12587 KRAS Gene Variants with Colorectal Cancer in a Mexican Population and Their Analysis In Silico.

Cells - 26 Jul 2023

Gallegos-Arreola Martha Patricia, Garibaldi-Ríos Asbiel Felipe, Cruz-Sánchez José Israel, Figuera Luis Eduardo, Ronquillo-Carreón Carlos Alberto, Rosales-Reynoso Mónica Alejandra, Gómez-Meda Belinda Claudia, Carrillo-Dávila Irving Alejandro, Puebla-Pérez Ana María, Montoya-Fuentes Héctor, Peralta-Leal Valeria, Zúñiga-González Guillermo M

Abstract excerpt

Colorectal cancer (CRC) is a major global health challenge and one of the top 10 cancers in Mexico. Lifestyle and genetic factors influence CRC development, prognosis, and therapeutic response; identifying risk factors, such as the genes involved, is critical to understanding its behavior, mechanisms, and prognosis. The association between KRAS gene variants (rs8720 and rs12587) and CRC in the Mexican population...

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PMID: 37566020
DOI: 10.3390/cells12151941
PMCID: PMC10417115

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