Article
TCF7L2, CASC8, and GREM1 polymorphism and colorectal cancer in south-eastern Romanian population.
Medicine - 17 Feb 2023
Mitroi Anca Florentina, Leopa Nicoleta, Dumitru Eugen, Dumitru Andrei, Tocia Cristina, Popescu Ioana, Mitroi Adrian, Popescu Răzvan Cătălin
Abstract excerpt
Colorectal cancer (CRC) is a heterogeneous disease with an increasing trend and with multiple epigenetic alterations and different molecular features, a major cause of mortality and morbidity. The Wnt/β-Catenin pathway is involved in multiple aspects of cell dynamics, architecture of developing gastrointestinal tissues, and intestinal tissue homeostasis in adults, but its aberrant activity plays an important role...
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