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A new discovery of genetic polymorphisms of important genes in WNT pathway (LPR5 and AXIN1) associated with osteoporosis susceptibility in Chinese Han population

2021-03-16

Abstract excerpt

<h4>Background: </h4> genetic factors play a critical role in the pathogenesis of osteoporosis. The imbalance of WNT/β-catenin will cause the occurrence of osteoporosis. LPR5 and AXIN1 play an important role in the classical Wnt/β-catenin signaling pathway. Our study was aimed to determine the association between 5 candidate single nucleotide polymorphisms (SNPs) of LPR5 or AXIN1 and osteoporosis susceptibility in...

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Literature Corpus work
d907ad97-8552-5fab-bb06-1af1a8813ab5
DOI
10.21203/rs.3.rs-289677/v1
Open publication

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A new discovery of genetic polymorphisms of important genes in WNT pathway (LPR5 and AXIN1) associated with osteoporosis susceptibility in Chinese Han populationDOI 10.21203/rs.3.rs-289677/v1
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