Article
AXIN2 polymorphism and its association with prostate cancer in a Turkish population.
Medical oncology (Northwood, London, England) - 1 Dec 2011
Pinarbasi Ergun, Gunes Emine Gulsen, Pinarbasi Hatice, Donmez Gonca, Silig Yavuz
Abstract excerpt
Polymorphism of AXIN2, a component of Wnt signaling, has been shown to play a role in tumorigenesis and dysregulated in cancer cells. In order to find out if AXIN2 polymorphism is a risk factor for prostate cancer, we analyzed eight polymorphic regions of this gene in 84 patients with prostate cancer and compared the results with 100 healthy controls in a Turkish population using PCR-RFLP methods. The genotype...
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