Article
Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia.
Human molecular genetics - 8 Apr 2024
Ochs-Balcom Heather M, Preus Leah, Du Zhaohui, Elston Robert C, Teerlink Craig C, Jia Guochong, Guo Xingyi, Cai Qiuyin, Long Jirong, Ping Jie, Li Bingshan, Stram Daniel O, Shu Xiao-Ou, Sanderson Maureen, Gao Guimin, Ahearn Thomas, Lunetta Kathryn L, Zirpoli Gary, Troester Melissa A, Ruiz-Narváez Edward A, Haddad Stephen A, Figueroa Jonine, John Esther M, Bernstein Leslie, Hu Jennifer J, Ziegler Regina G, Nyante Sarah, Bandera Elisa V, Ingles Sue A, Mancuso Nicholas, Press Michael F, Deming Sandra L, Rodriguez-Gil Jorge L, Yao Song, Ogundiran Temidayo O, Ojengbede Oladosu, Bolla Manjeet K, Dennis Joe, Dunning Alison M, Easton Douglas F, Michailidou Kyriaki, Pharoah Paul D P, Sandler Dale P, Taylor Jack A, Wang Qin, O'Brien Katie M, Weinberg Clarice R, Kitahara Cari M, Blot William, Nathanson Katherine L, Hennis Anselm, Nemesure Barbara, Ambs Stefan, Sucheston-Campbell Lara E, Bensen Jeannette T, Chanock Stephen J, Olshan Andrew F, Ambrosone Christine B, Olopade Olufunmilayo I, The Ghana Breast Health Study Team, Conti David V, Palmer Julie, García-Closas Montserrat, Huo Dezheng, Zheng Wei, Haiman Christopher
Abstract excerpt
BACKGROUND: Expansion of genome-wide association studies across population groups is needed to improve our understanding of shared and unique genetic contributions to breast cancer. We performed association and replication studies guided by a priori linkage findings from African ancestry (AA) relative pairs. METHODS: We performed fixed-effect inverse-variance weighted meta-analysis under three significant AA...
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