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T Cells in Celiac Disease

1 Apr 2017

Abstract excerpt

Celiac disease is a human T cell-mediated autoimmune-like disorder caused by exposure to dietary gluten in genetically predisposed individuals. This review will discuss how CD4 T cell responses directed against an exogenous Ag can cause an autoreactive B cell response and participate in the licensing of intraepithelial lymphocytes to kill intestinal epithelial cells. Furthermore, this review will examine the...

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PMID: 28373482
DOI: 10.4049/jimmunol.1601693

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