Article
Gluten-dependent intestinal autoimmune response.
Current pharmaceutical design - 1 Jan 2012
Korponay-Szabó Ilma Rita, Simon-Vecsei Zsafia, De Leo Luigina, Not Tarcisio
Abstract excerpt
Celiac disease is a multi-systemic autoimmune disease of the small bowel induced by gluten in genetically predisposed subjects. Highly specific and gluten-dependent production of auto-antibodies targeting self-proteins of the transglutaminase family occurs in the intestinal mucosa. These anti-transglutaminase antibodies are found deposited in intestinal and extra-intestinal tissue where they might exert...
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