Article
Tissue-mediated control of immunopathology in coeliac disease.
Nature reviews. Immunology - 1 Dec 2009
Jabri Bana, Sollid Ludvig M
Abstract excerpt
Coeliac disease is an inflammatory disorder with autoimmune features that is characterized by destruction of the intestinal epithelium and remodelling of the intestinal mucosa following the ingestion of dietary gluten. A common feature of coeliac disease and many organ-specific autoimmune diseases is a central role for T cells in causing tissue destruction. In this Review, we discuss the emerging hypothesis that,...
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