Transcriptomic profiling of healthy individual-derived LCLs revealed inter-individual variability towards-hypoxia-responsive pathways

Abstract excerpt

Hypoxia, or low oxygen levels, affects various developmental, physiological, and pathological processes. It’s been consistently reported that there is an inter-individual variability at genetic and molecular pathways related to oxygen sensing and response. Understanding the underlying variability towards hypoxia sensing and response in health and disease conditions is challenging. The Prakriti stratification meth...

Topics

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• Autophagy in Disease and Therapy
• Cancer, Hypoxia, and Metabolism
• Cell Respiration
• Gene Expression Profiling
• Gene Expression Regulation
• Mitochondrial Function and Pathology
• Molecular Sequence Annotation
• Oxygen Consumption

Identifiers and source

Literature Corpus work

3f00e1a3-b1e2-5005-bb6a-6d418b68cfbb

DOI

10.1101/2024.08.06.606933