Article
Platform for combined analysis of functional and biomolecular phenotypes of the same cell.
Scientific reports - 16 Mar 2017
Kelbauskas L, Ashili S, Zeng J, Rezaie A, Lee K, Derkach D, Ueberroth B, Gao W, Paulson T, Wang H, Tian Y, Smith D, Reid B, Meldrum Deirdre R
Abstract excerpt
Functional and molecular cell-to-cell variability is pivotal at the cellular, tissue and whole-organism levels. Yet, the ultimate goal of directly correlating the function of the individual cell with its biomolecular profile remains elusive. We present a platform for integrated analysis of functional and transcriptional phenotypes in the same single cells. We investigated changes in the cellular respiration and...
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