Article
Association of the HLA-B*53:01 Allele With Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome During Treatment of HIV Infection With Raltegravir.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 May 2017
Thomas Mark, Hopkins Chris, Duffy Eamon, Lee Daniel, Loulergue Pierre, Ripamonti Diego, Ostrov David A, Phillips Elizabeth
Abstract excerpt
Background: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare, severe adverse event during treatment with raltegravir. The occurrence of DRESS syndrome during treatment with other drugs is strongly associated with particular HLA alleles. Methods: We performed HLA testing in 3 of the 5 patients previously reported to have developed raltegravir-induced DRESS syndrome and in 1...
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