Article
The Antigen-Presenting Potential of Vγ9Vδ2 T Cells During Plasmodium falciparum Blood-Stage Infection.
The Journal of infectious diseases - 15 May 2017
Howard Jennifer, Loizon Séverine, Tyler Christopher J, Duluc Dorothée, Moser Bernhard, Mechain Matthieu, Duvignaud Alexandre, Malvy Denis, Troye-Blomberg Marita, Moreau Jean-Francois, Eberl Matthias, Mercereau-Puijalon Odile, Déchanet-Merville Julie, Behr Charlotte, Mamani-Matsuda Maria
Abstract excerpt
During Plasmodium falciparum infections, erythrocyte-stage parasites inhibit dendritic cell maturation and function, compromising effective antimalarial adaptive immunity. Human Vγ9Vδ2 T cells can act in vitro as antigen-presenting cells (APCs) and induce αβ T-cell activation. However, the relevance of this activity in vivo has remained elusive. Because Vγ9Vδ2 T cells are activated during the early immune...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
