Article
Phenotypic profiling of CD8(+) T cells during Plasmodium vivax blood-stage infection.
BMC infectious diseases - 31 Jan 2015
Hojo-Souza Natália Satchiko, Pereira Dhelio Batista, Passos Lívia Silva Araújo, Gazzinelli-Guimarães Pedro Henrique, Cardoso Mariana Santos, Tada Mauro Shugiro, Zanini Graziela Maria, Bartholomeu Daniella Castanheira, Fujiwara Ricardo Toshio, Bueno Lilian Lacerda
Abstract excerpt
BACKGROUND: For a long time, the role of CD8(+) T cells in blood-stage malaria was not considered important because erythrocytes do not express major histocompatibility complex (MHC) class I proteins. While recent evidences suggest that CD8(+) T cells may play an important role during the erythrocytic phase of infection by eliminating parasites, CD8(+) T cells might also contribute to modulate the host response...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.