Article
Heterotrimeric G proteins in the control of parathyroid hormone actions.
Journal of molecular endocrinology - 1 May 2017
Bastepe Murat, Turan Serap, He Qing
Abstract excerpt
Parathyroid hormone (PTH) is a key regulator of skeletal physiology and calcium and phosphate homeostasis. It acts on bone and kidney to stimulate bone turnover, increase the circulating levels of 1,25 dihydroxyvitamin D and calcium and inhibit the reabsorption of phosphate from the glomerular filtrate. Dysregulated PTH actions contribute to or are the cause of several endocrine disorders. This calciotropic...
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