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Article

Genetic variations in the alanine-glyoxylate aminotransferase 2 (AGXT2) gene and dimethylarginines levels in rheumatoid arthritis.

Amino acids - 1 Jun 2017

Dimitroulas Theodoros, Hodson James, Panoulas Vasileios F, Sandoo Aamer, Smith Jacqueline, Kitas George

Abstract excerpt

Rheumatoid arthritis (RA) is associated with high rates of cardiovascular events mainly due to coronary and cerebrovascular atherosclerotic disease. Asymmetric (ADMA) and symmetric (SDMA) dimethylarginines are endogenous inhibitors of nitric oxide synthase and have been repeatedly linked with adverse cardiovascular outcomes in the general population and various disease settings. Alanine-glyoxylate...

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Identifiers

PMID: 28357606
DOI: 10.1007/s00726-017-2413-6

Genes

AGXT2
AGXT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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