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Article

SMARCAD1 Contributes to the Regulation of Naive Pluripotency by Interacting with Histone Citrullination.

Cell reports - 28 Mar 2017

Xiao Shu, Lu Jia, Sridhar Bharat, Cao Xiaoyi, Yu Pengfei, Zhao Tianyi, Chen Chieh-Chun, McDee Darina, Sloofman Laura, Wang Yang, Rivas-Astroza Marcelo, Telugu Bhanu Prakash V L, Levasseur Dana, Zhang Kang, Liang Han, Zhao Jing Crystal, Tanaka Tetsuya S, Stormo Gary, Zhong Sheng

Abstract excerpt

Histone citrullination regulates diverse cellular processes. Here, we report that SMARCAD1 preferentially associates with H3 arginine 26 citrullination (H3R26Cit) peptides present on arrays composed of 384 histone peptides harboring distinct post-transcriptional modifications. Among ten histone modifications assayed by ChIP-seq, H3R26Cit exhibited the most extensive genomewide co-localization with SMARCAD1...

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Identifiers

PMID: 28355564
DOI: 10.1016/j.celrep.2017.02.070
PMCID: PMC5466819

Genes

SMARCAD1
LIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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