Article
Short article: Impact of genetic variation in the vasopressin 1a receptor on the development of organ failure in patients admitted for acute decompensation of liver cirrhosis.
European journal of gastroenterology & hepatology - 1 May 2017
Kerbert Annarein J C, Schaapman Jelte J, van der Reijden Johan J, Amorós Navarro Àlex, McCormick Aiden, van Hoek Bart, Arroyo Vicente, Ginès Pere, Jalan Rajiv, Vargas Victor, Stauber Rudolf, Verspaget Hein W, Coenraad Minneke J
Abstract excerpt
BACKGROUND: Vasopressin receptor-mediated vasoconstriction is considered to be involved in the pathogenesis of organ failure in acute-on-chronic liver failure (ACLF). PATIENTS AND METHODS: We studied the association between six single nucleotide polymorphisms (SNPs) of the vasopressin 1a receptor gene and the development of organ failure in 826 patients admitted for acute decompensation of liver cirrhosis (n=641)...
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