Article
Study of V1a vasopressin receptor gene single nucleotide polymorphisms in platelet vasopressin responsiveness.
Journal of clinical laboratory analysis - 1 Jan 2006
Hasan Kazi N, Shoji Masaru, Tsutaya Shoji, Kudo Ryoko, Matsuda Eriko, Saito Junko, Kimura Tokihisa, Yasujima Minoru
Abstract excerpt
There is a significant heterogeneity among individuals in terms of platelet aggregation response to arginine vasopressin (AVP). The aim of this study was to evaluate whether four single nucleotide polymorphisms (SNPs) in the promoter region of vasopressin V1a receptor gene (V1aR) could be used as genetic markers for divergent platelet aggregation response to AVP. Seventeen of 33 subjects showed more than 60% of...
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